Each 5 ml ampoule contains 20 mg/ml iron as iron sucrose corresponding to 100 mg iron per ampoule.
Venofer® is indicated for the treatment of iron deficiency in following indications:
|Where there is a clinical need for a rapid iron supply,|
|In patients who cannot tolerate oral iron therapy or who are non-compliant,|
|In active inflammatory bowel disease where oral iron preparations are ineffective.|
Calculation of dosage:
The dosage has to be individually adapted according to the total iron deficit calculated with the following formula: Total iron deficit [mg] = body weight [kg] x (target Hb - actual Hb) [g/dl] x 2.4* + depot iron [mg]
If the quantity of blood lost is known:
The administration of 200 mg IV iron (=10 ml Venofer®) results in an increase in hemoglobin which is equivalent to 1 unit blood (=400 ml with 150 g/l Hb content).
|Two Venofer ampoules may be diluted in 100 ml 0.9% NaCl.|
|First 25 ml should be infused as a test dose over a period of 30 minutes at the rate of 12 drops/min|
|If no adverse reaction occurs during this time then the remaining portion of the infusion i.e. 75 ml, should be given at the rate of 36 drops /min.|
The use of Venofer® is contra-indicated in cases of:
|Anemia not caused by iron deficiency|
|Iron overload or disturbance in utilization of iron|
|Known hypersensitivity to Venofer® or any of its inactive components.|
|Pregnancy first Trimester.|
Ampoules (5 ml) containing 100 mg of iron: box of 5 ampoules.